Link Between Vitamin D and Dementia Risk Confirmed
In the largest study of its kind, researchers suggests that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer’s disease.
The study, published in the online edition of the journal Neurology, looked at blood levels of vitamin D, which includes vitamin D from food, supplements, and sun exposure. Dietary vitamin D is found in fatty fish such as salmon, tuna or mackerel, and milk, eggs, and cheese.
“We expected to find an association between low vitamin D levels and the risk of dementia and Alzheimer’s disease, but the results were surprising — we actually found that the association was twice as strong as we anticipated,” said David J. Llewellyn, PhD, University of Exeter Medical School, Exeter, United Kingdom.
For the study, 1,658 people aged older than 65 years who were dementia-free had their vitamin D blood levels tested. After an average of 6 years, 171 participants developed dementia and 102 had Alzheimer’s disease.
The study found that people with low levels of vitamin D had a 53% increased risk of developing dementia and those who were severely deficient had a 125% increased risk compared with participants with normal levels of vitamin D.
People with lower levels of vitamin D were nearly 70% more likely to develop Alzheimer’s disease and those who had severe deficiency were over 120% more likely to develop the disease.
The results remained the same after researchers adjusted for other factors that could affect risk of dementia, such as education, smoking, and alcohol consumption.
“Clinical trials are now needed to establish whether eating foods such as oily fish or taking vitamin D supplements can delay or even prevent the onset of Alzheimer’s disease and dementia,” said Dr. Llewellyn. “We need to be cautious at this early stage and our latest results do not demonstrate that low vitamin D levels cause dementia. That said, our findings are very encouraging, and even if a small number of people could benefit, this would have enormous public health implications given the devastating and costly nature of dementia.”
by DG News
Source: American Academy of Neurology